Alan Davies will be back in the title role, with Sheridan Smith reprising her role as fellow investigator Joey Ross. Rik Mayall will also return to the series as DI Gideon Pryke, a character last seen in 1998 episode 'Black Canary'.
Guest stars in 'Savant's Thumb' include Sarah Alexander (Green Wing), Joanna Lumley (Absolutely Fabulous), Nigel Planer (The Young Ones) and Hasina Haque (Casualty).
The 90-minute special will see Creek and Ross drawn into a complex case involving a secret society, strange events at a girls' boarding school, and the miraculous disappearance of a body in front of three witnesses.
Filming is currently underway on the episode, which has been written and directed by the show's creator David Renwick.