When asked how he would introduce himself to a woman, Efron joked: "'So, do you like High School Musical?' I'm kidding!"
He continued: "If the situation's right, buy someone a drink. Think on your toes, use what's around you, and come up with something organic and fun."
The star, who previously dated High School Musical co-star Vanessa Hudgens and has recently been linked to Mirror Mirror actress Lily Collins, also revealed the best comment he has been given by an admirer.
"A woman called me interesting once, and it kind of blew my mind," he explained.
"She said, 'You're one of the most interesting people I've ever met', and I was like, 'Wow'. I'm still high on that one."
Efron is currently starring in The Lucky One with Taylor Schilling, portraying a marine who believes finding the picture of a beautiful blonde woman was the reason for his safe return from a tour of Iraq.
Watch Zac Efron introduce the trailer for The Lucky One for Digital Spy below: